Home Science Scientists accidentally reprogram mature mouse GABA neurons into dopaminergic-like neurons

Scientists accidentally reprogram mature mouse GABA neurons into dopaminergic-like neurons

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Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells. Their findings reveal that — contrary to previous belief — it is possible to reprogram one mature neuron type into another without first reverting it to a stem-cell-like state.