The spike protein on the novel coronavirus that helps it break into healthy cells has a tiny “pocket” that could make it vulnerable to antiviral drugs, researchers have discovered. In a paper published on Monday in Science, researchers note that common-cold-causing rhinoviruses have a similar pocket, and drugs that fit into the pocket by mimicking fatty acids like LA have lessened symptoms in human clinical trials. This suggests, they say, that drugs developed to target the pocket on the coronavirus spike protein might help eliminate COVID-19.
