Home Science Immune cells destroy healthy brain connections, diminish cognitive function in obese mice

Immune cells destroy healthy brain connections, diminish cognitive function in obese mice

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Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice. The research suggests that microglia may be a potential therapeutic target for one of the lesser known effects of this global health epidemic on the brain.