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A new therapeutic avenue for treating insomnia

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Insomnia is one of the major sleep problems all over the world. However, the most widely prescribed medicines for the treatment of insomnia are plagued by a wide range of adverse effects. Researchers have succeeded in identifying the first positive allosteric modulator for adenosine A2A receptors and found that it induces sleep without affecting cardiovascular function, unlike classic receptor agonists. Their discovery may unlock the development of the next-generation sleeping pill.