British Prime Minister Boris Johnson is set to hold a news conference alongside his top scientific advisers Saturday amid anticipation of him announcing a new national lockdown for England to stem a resurgence of the coronavirus. London School of Hygiene epidemiologist John Edmunds, a member of the government’s scientific advisory group, said Saturday that cases were running “significantly above” a reasonable worst-case scenario drawn up by modelers. “It is really unthinkable now, unfortunately, that we don’t count our deaths in tens of thousands from this wave,” Edmunds told the BBC.