What if we could identify proteins as easily as we can sequence DNA and RNA? Perhaps soon we will, thanks to new DNA Nanoswitch Calipers. DNA Calipers create a unique ‘fingerprint’ for peptides (the building blocks of proteins) by repeatedly applying force to them to generate a series of distance measurements for each peptide. This innovation opens up a new avenue for pursuing the goal of single-cell proteomics, and enables potentially life-saving discoveries in human health and disease.
