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T cell behavior determines which tumors respond to treatment

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Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn’t work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant tumors, the genetic program of those T cells and the developmental path they then follow, may affect their response to immunotherapy and predict overall patient survival, according to a new study. The results overturn the prevailing model of immune responses in melanoma and present different therapeutic approaches.

Source: ScienceDaily.com