Home Science Androgen receptor, treatment target for prostate cancer, imports into mitochondria

Androgen receptor, treatment target for prostate cancer, imports into mitochondria

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Androgens stimulate prostate cancer cells to grow. Many drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor, or AR. Researchers have discovered a new function of the AR in prostate cells — the AR is imported into and localizes to mitochondria of the cell, where it plays a novel role in regulating multiple mitochondrial processes.